Focused radiation for breast cancer that is mostly stable
Part of Cancer, Skin clinical trials.
This study tests whether giving focused radiation (SABR) to a few growing spots of breast cancer, while continuing your current hormone therapy and CDK 4/6 inhibitor, can help control the cancer longer than switching to a different treatment. It is for people whose cancer is mostly stable but has a small number of spots that have started to grow.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and have breast cancer that has spread (advanced breast cancer).
- Your cancer type is called ER-positive and HER2-negative (hormone-sensitive).
- You have been on a hormone therapy pill or injection plus a CDK 4/6 inhibitor (like palbociclib, ribociclib, or abemaciclib) for at least 6 months, and your cancer has mostly stayed stable or shrunk.
- The cancer has grown or appeared in only 1 to 5 places (like in the lung, liver, or bones), and those spots can be safely treated with focused radiation.
- You have not had chemotherapy for cancer that has spread beyond the breast, and any brain metastases are stable.
- You are fit enough to take part, with a performance status of 0-2 (meaning you can do most daily activities).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether treating each spot of cancer that has spread (but only a few spots) with focused radiation can help control breast cancer. It aims to see if this approach can stop the cancer from growing further without needing strong whole-body treatments right away.
This Phase 2 study tests whether adding a very focused type of radiation to standard drug treatment can better control metastatic breast cancer. It is for people whose cancer is only progressing in one spot, seen on a PET scan.
This trial looks at whether giving radiation treatment to tumors in people with a limited number of metastases can help control the cancer. It is for adults with certain cancer types that have spread to specific organs, and who can manage daily activities with little or no help.
This trial tests a precise, high-dose radiation technique (SABR) for people whose cancer has started to grow again in only a few spots despite ongoing medication. The goal is to control those new growths while continuing your current treatment.
This trial tests whether adding focused, high-dose radiation (SABR) to standard drug therapy can better control cancer that has spread to a few spots in the body. It is for people starting or resuming cancer medicines for newly found or growing metastases.
This study tests whether a focused, high-precision type of radiation can control many cancer spread-out spots (“metastases”) at the same time, while keeping side effects acceptable. It may help people with many metastases live longer or have better disease control by aiming treatment at every treatable spot.
Hear when a new Metastatic Breast Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.