Testing SABR radiation plus current therapy for slow-growing breast cancer spots
Part of Cancer, Skin clinical trials.
This trial tests whether adding a precise, high-dose radiation (called SABR) to your current targeted therapy can control a few growing spots of advanced breast cancer better than switching to a different drug. It is for people with ER-positive, HER2-negative breast cancer whose cancer has been well controlled for at least 6 months but now has 1–5 spots that are starting to grow.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have ER-positive, HER2-negative advanced breast cancer and are currently on endocrine therapy plus a CDK4/6 inhibitor (like palbociclib).
- Your cancer has been stable or responding to this treatment for at least 6 months.
- You have 1 to 5 spots of cancer that have started to grow again (oligoprogression) that can be targeted with SABR radiation.
- You are willing to keep taking your current treatment during the study.
- You can complete quality-of-life questionnaires and have an expected survival of at least 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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