Clin2
NCT06590857Possibly a fitRecruiting

Study of targeted radiation for advanced breast cancer

Metastatic Breast CancerHER2-negative Breast CancerER+ Breast CancerAdvanced Breast CancerMetastatic Breast Cancer With Bone InvolvementBone Metastases in Subjects With Advanced Breast CancerER-Positive HER2-Negative Breast CancerEstrogen Receptor-positive Breast Cancer

Part of Cancer, Skin clinical trials.

This trial tests a new type of radiation therapy that targets a specific protein on some breast cancer cells. It may help people whose cancer has stopped responding to other treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
64 people
Ages
Any age
Study type
Interventional

Who can take part

  • Your breast cancer must be estrogen receptor-positive (ER+) and HER2-negative, and it has spread or cannot be removed with surgery.
  • You need to have adequate kidney, liver, and blood cell function.
  • Depending on the study group, you must have tried certain prior treatments (like chemotherapy or CDK4/6 inhibitors).
  • Your cancer must show the targeted protein on imaging tests (SSTR-PET).
  • If you have bone-only or bone-dominant disease, you can join the combination group, but you cannot have liver metastases or symptomatic organ disease.
  • You cannot have had prior radiopharmaceutical therapy (like radioembolization).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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