Short IV antibiotics vs switch to oral in young UTI children
Part of Infections, Kidney & urinary clinical trials.
This trial tests whether giving antibiotics through a vein for 3 days works as well as giving 3 days through a vein followed by 7 days by mouth for a first urinary tract infection (kidney infection). It may help your child recover safely while possibly reducing longer IV treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is at least 1 month old and younger than 3 years (with extra rules for those under 3 months).
- This is the child’s first urinary tract infection, confirmed by urine findings and a urine culture.
- The urine must be collected properly (not using a urine bag).
- Your child’s infection must be treated starting with ceftriaxone and/or amikacin (given as the first antibiotics).
- The bacteria must be one main type, sensitive to the starting antibiotic, and also sensitive to cefixime or cotrimoxazole.
- Your child must have no kidney abscess on ultrasound and no certain kidney/urinary birth differences.
- You (the parent/guardian) must be able to give written consent and have reliable follow-up at the study center.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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