Single IV antibiotic dose for complicated UTIs in children
Part of Infections clinical trials.
This trial studies whether giving just one dose of an intravenous (IV) antibiotic can safely treat complicated urinary tract infections (UTIs) in children. It aims to see if this shorter approach works as well as standard treatment while still preventing complications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is 3 months (corrected for age) to 18 years old
- They have a fever with this current illness, and the emergency doctor thinks it’s a UTI needing IV antibiotics
- They have signs that make the UTI “complicated,” such as vomiting, chills/shaking (rigors), repeated UTIs, urinary tract problems, or a fast heart rate
- A urine sample is available for testing soon, including a urine culture collected before or within about 1 hour of starting antibiotics
- Urine test shows signs of infection (like nitrite positive or higher white blood cells) and/or the culture/imaging supports a kidney infection
- They do NOT have a reason to avoid IV antibiotics in this trial, like severe infection (sepsis) or an allergy to the study medicines
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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