Clin2
NCT05597540Possibly a fitRecruiting

Shorter antibiotics for kidney transplant kidney infections

Pyelonephritis AcuteKidney Transplant Infection

Part of Infections, Kidney & urinary clinical trials.

This study compares giving antibiotics for 7 days versus 14 days to treat acute kidney infections (pyelonephritis) in people with kidney transplants. It aims to see if the shorter course works just as well and is safer or easier to complete.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
470 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are over 18 and have a kidney transplant
  • You have a kidney infection with fever (at least 38°C) plus urine signs of infection, and your urine culture grows bacteria that match the antibiotic plan
  • There is no other confirmed or suspected fever-causing infection besides the urine infection
  • Your early response to the first antibiotic is improving within 48–60 hours (fever goes below 38°C and urine symptoms improve)
  • Imaging (scan) before treatment shows no blockage and no abscess
  • You can sign consent and follow the study rules

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07407673Not yet recruiting· Phase 3
Preventing blood infections after kidney transplant

This study tests whether giving an antibiotic after a kidney transplant can prevent bloodstream infections. Participants who have bacteria in their urine in the first month after transplant may be eligible.

Aarhus
NCT05544565Recruiting· Phase 4
Short IV antibiotics vs switch to oral in young UTI children

This trial tests whether giving antibiotics through a vein for 3 days works as well as giving 3 days through a vein followed by 7 days by mouth for a first urinary tract infection (kidney infection). It may help your child recover safely while possibly reducing longer IV treatment.

Corbeil-Essonnes, Essonne
NCT07765615Not yet recruiting
Personalized antibiotic dosing after kidney transplant

This study looks at giving anti-infection medications (antibiotics) in a more personalized way soon after a kidney transplant. By carefully adjusting the dose, doctors hope to prevent infections while keeping the new kidney safe.

NCT07106125Not yet recruiting· Phase 4
Extended antibiotics after kidney transplant

This study looks at whether continuing an antibiotic called TMP-SMX (Bactrim) for longer helps prevent urinary tract infections after a kidney transplant. If you've already taken it safely for 6 months, you may qualify to continue it for another 6 months or stop, to see which is better.

San Francisco, California
NCT04291768Recruiting· Phase 4
Shorter 5-day antibiotics for certain gram-negative bloodstream infections

This trial tests whether people with a specific type of bloodstream infection caused by gram-negative bacteria can safely take antibiotics for only 5 days instead of longer. It may help by reducing antibiotic exposure if your infection source is controlled quickly.

Aalborg
NCT06409819Recruiting· Phase 1/Phase 2
Phage therapy for recurrent UTIs in kidney transplant patients

This trial tests a phage (virus that kills bacteria) treatment for women who have had a kidney transplant and keep getting urinary tract infections (UTIs) caused by E. coli bacteria. It aims to see if this therapy can help prevent future infections.

La Jolla, California

Hear when a new Pyelonephritis Acute trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.