Chemo and radiation before surgery versus chemo alone for esophageal cancer
Part of Cancer, Digestive system clinical trials.
This trial studies whether adding radiation to chemotherapy before surgery works better for people with operable (resectable) squamous cell esophageal cancer. It aims to improve outcomes by comparing two different treatment plans before the operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed squamous cell cancer of the esophagus (proven by pathology/biopsy).
- Your cancer is operable and classified as stage cT1-4a, N1-3, and M0 (no distant metastasis).
- You are well enough for cancer treatment and surgery (ECOG performance status 0–1).
- Your age is 18 to 70 years.
- Your blood counts, liver, kidney, and heart function are strong enough to safely receive treatment (specific lab cutoffs are required).
- You have no major reasons to avoid study medicines like paclitaxel, carboplatin, docetaxel, cisplatin, or fluorouracil (no known allergy/contraindication).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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