Non-surgical treatment for bile duct cancer using heat or light
Part of Cancer, Digestive system clinical trials.
This trial tests whether treating hilar bile duct cancer with either radiofrequency ablation (heat) or photodynamic therapy (light-activated medicine) can help patients when surgery isn’t an option. It aims to treat the tumor directly without planned surgery soon.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed hilar cholangiocarcinoma (bile duct cancer) by test results (cell or tissue).
- You are 18 years or older.
- A doctor does not plan any surgery for you.
- The tumor can be reached using an endoscope (a scope passed through the body).
- You can give written informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new combination of immunotherapy (tislelizumab), radiation, and chemotherapy before surgery for people with bile duct cancer that is hard to remove. The goal is to shrink the tumor enough to allow successful surgery.
This trial tests a combination of a drug (durvalumab) that helps your immune system fight cancer, plus a special heat treatment applied inside the bile duct. It is for people with bile duct cancer that cannot be removed by surgery and who need a stent to open the bile duct.
This trial tests a light-based treatment called photodynamic therapy (PDT) given before surgery for bile duct cancer. The goal is to see if this approach can help shrink the tumor and make surgery more effective.
This trial tests a procedure that uses heat (radiofrequency ablation) to treat bile duct cancer that can't be removed by surgery. If you have this type of cancer and are starting standard treatment, this study wants to see if adding this heat treatment is safe and might help.
This trial is testing a new approach for people with bile duct cancer that cannot be removed by surgery. It combines a procedure that uses heat to destroy cancer cells inside the bile duct with standard radiation therapy.
This trial tests a combination of heat therapy inside the bile duct (endobiliary RFA) with immunotherapy (durvalumab) and chemotherapy (gemcitabine and cisplatin) for people with unresectable extrahepatic cholangiocarcinoma. The goal is to see if adding the heat treatment improves outcomes.
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