Combination therapy for persistent low-level acute myeloid leukemia
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a combination of drugs for people with AML who, after initial treatment, have very low levels of leukemia still present (called measurable residual disease or MRD). The goal is to wipe out these remaining cells and reduce the chance of the cancer coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 59 years old.
- You were treated for AML (a type of blood cancer) with initial chemotherapy and achieved remission (cancer is gone from blood counts) but still have very small amounts of disease left (called MRD).
- You were part of the myeloMATCH study for your first treatment.
- You do not have a specific gene change called FLT3 mutation.
- You can swallow oral tablets and your organ functions (liver, kidney, etc.) are within acceptable limits.
- You are not pregnant or breastfeeding, and you agree to use effective contraception during and after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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