Comparing two drug combos for adults with FLT3-ITD AML
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a new combination of medications against a standard treatment for adults with a specific type of acute myeloid leukemia (AML) that has a FLT3-ITD mutation. The goal is to find out if the new combination works better and has fewer side effects. If you have this type of AML, you might be able to join and get access to newer drugs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 59 years old.
- You have been newly diagnosed with acute myeloid leukemia (AML) that has a FLT3-ITD mutation.
- You have not had prior treatment for AML, except for managing symptoms.
- You are generally well enough to carry out daily activities (ECOG 0-2).
- You have adequate liver, kidney, and heart function (checked by blood tests and an echocardiogram).
- You are not pregnant or breastfeeding, and you agree to use effective birth control during and after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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