Clin2
NCT05570448Possibly a fitRecruiting

Endoscopy treatment using APC for chronic reflux disease

Gastro Esophageal Reflux

Part of Digestive system clinical trials.

This trial studies whether an endoscopy procedure using APC (a type of heat/energy treatment) can improve symptoms in people with chronic GERD and confirmed acid reflux. It may help reduce reflux-related discomfort for people who meet specific testing and safety requirements.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
36 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You have had GERD symptoms for at least 6 months, with heartburn or acid reflux/regurgitation at least twice per week
  • You have confirmed acid reflux on an ambulatory pH test
  • You are willing and able to consent and participate in the study
  • You must be between 18 and 80 years old
  • You should NOT be unable to take proton pump inhibitors (PPIs) due to allergy or intolerance

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06641375Recruiting
Heat treatment for chronic acid reflux (AREA study)

This trial tests a new way to treat GERD (chronic acid reflux) using a tiny camera and a device that delivers a gentle heat treatment (argon plasma coagulation) to the area where the stomach meets the esophagus. It's compared to a 'sham' procedure (you won't know which you get) to see if it stops acid from backing up better than medicine alone.

Hyderabad, Telangana
NCT06106100Not yet recruiting
Endoscopic treatment for ongoing acid reflux symptoms

This trial tests a new endoscopic procedure called anti-reflux mucosal ablation therapy to reduce acid reflux in people who still have symptoms despite taking acid-reducing medication. The goal is to see if this treatment helps improve heartburn and related symptoms.

NCT04065516Enrolling by invitation
Test for reflux treatment after POEM for achalasia

This study looks at a specific treatment (“ARAT”) to help people who develop acid reflux after a procedure called POEM for achalasia. It may help reduce reflux symptoms and abnormal acid levels in the stomach/esophagus after the original procedure.

Mexico City, Mexico City
NCT06348420Recruiting
New procedure vs. acid-reducing pills for GERD

This study compares a new procedure called anti-reflux mucosal valvuloplasty (ARMV) to acid-reducing medicines (PPIs) for treating GERD. It may help people who have had reflux for a long time and need daily PPIs.

Jinan, Shandong
NCT07010107Recruiting· Phase 3
Testing anaprazole for moderate to severe reflux esophagitis

This trial tests a new medicine called anaprazole for people with moderate to severe reflux esophagitis (chronic heartburn and damage to the food pipe). It compares anaprazole to a standard treatment to see which works better and is safer.

Shanghai, Shanghai Municipality
NCT07176221Not yet recruiting
Endoscopic procedure for stubborn acid reflux

This study tests a new endoscopic procedure to help people with severe acid reflux that hasn't improved with strong medications. The procedure tightens the valve between the stomach and esophagus to reduce acid backing up.

Shenzhen, Guangdong

Hear when a new Gastro Esophageal Reflux trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.