Clinical trials
Gastro Esophageal Reflux clinical trials
Below are recruiting gastro esophageal reflux clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03596476Recruiting
Test for reflux causes after proton pump pills fail
This study checks whether a special test of the esophagus after meals can find the exact reason for ongoing reflux symptoms when proton pump pills (PPIs) don’t help. It may help doctors choose the right next treatment for people whose reflux symptoms keep coming back.
Chambray-lès-ToursAges 18 years+ - NCT04255693Recruiting
Real-life reflux study of diet and behavior changes
This study looks at how following specific diet and behavior changes affects symptoms of acid reflux (heartburn/regurgitation) in everyday life. It may help you understand what lifestyle steps improve reflux and how symptoms change over time.
MoscowAges 18–80 - NCT04312633Recruiting
Testing a new throat biopsy mapping method for Barrett’s disease
This study follows people for 5 years to see how well a new biopsy-mapping test (WATS3D) works during routine upper endoscopy. It may help doctors find Barrett’s esophagus changes earlier and better guide follow-up after treatment.
Bethpage, New YorkAges 18 years+ - NCT05066594Recruiting
Registry for a procedure to treat long-term reflux
This is an observational study (no experimental treatment) that follows people who choose a specific procedure called transoral incisionless fundoplication (TIF) with the EsophyX device for long-term acid reflux. It aims to track outcomes for up to 5 years at San Raffaele Hospital.
MilanAges 18–80 - NCT05132816Recruiting
Test manometry after partial anti-reflux surgery
This study checks how well a swallowing test called high-resolution manometry works after partial anti-reflux surgery. It focuses on adults with certain abnormal esophagus muscle patterns to help doctors understand what to expect after the operation.
Schlieren, Canton of ZurichAges 18 years+ - NCT05180253Recruiting
Registry study for healthy people to collect stomach and esophagus samples
This study enrolls healthy adults to build a registry and biobank (collection of samples). It tests whether collecting information and biological samples from people without symptoms can help researchers understand normal stomach and esophagus function.
Louisville, KentuckyAges 18–85 - NCT06564558Recruiting
Posture correction for GERD symptoms
This study tests whether teaching people with GERD to improve their posture can reduce their symptoms. It is for people with a rounded upper back (kyphosis) and a GERD diagnosis.
BeirutAges 18–60 - NCT06693622Recruiting
Patient preferences for Barrett's esophagus screening tests
This study asks people at risk for Barrett's esophagus (a condition that can lead to esophageal cancer) to share which screening test they prefer. Your answers help researchers understand what matters most to patients when choosing a screening method.
Aurora, ColoradoAges 18–89 - NCT07131397Recruiting
Breathing muscle training for GERD
This trial tests whether strengthening your breathing muscles can help reduce GERD symptoms. You may be eligible if you have GERD and are in generally good health without other major conditions.
Athens, AtticaAges 18–70 - NCT05678491Enrolling by invitation
Endoscopic treatment for reflux after gastric sleeve surgery
This trial studies an endoscopic procedure to treat gastroesophageal reflux disease (GERD) in people who had gastric sleeve surgery. It may help if reflux symptoms are not controlled on once-daily acid medicine (PPI) or if you cannot tolerate it and want an alternative.
TrondheimAges 18–70 - NCT07700342Recruiting
Could an evening gel improve sleep for nighttime reflux?
This trial tests a topical therapy you apply at night to see if it can improve sleep for people with non-erosive GERD who still have nighttime symptoms even while taking a morning acid reducer.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07482969Recruiting
GERD symptoms in Czech children study
This study asks children ages 8-9 and 12-13 about symptoms of gastroesophageal reflux disease (GERD), a condition where stomach acid flows back into the throat. It aims to understand how common these symptoms are.
PragueAges 8–13 - NCT05455359RecruitingPhase 4
Tube-fed children at high risk for aspiration pneumonia
This Phase 4 study looks at gastrointestinal movement (dysmotility) and how it may increase the risk of aspiration pneumonia in children who eat through a tube and have swallowing safety problems. It may help doctors better prevent lung infections in children who cough/choke and need suction often.
Boston, MassachusettsAges 5–21 - NCT03103789Enrolling by invitation
Testing a device that measures esophagus lining health
This study tests a new sensor to check how healthy the lining of your esophagus is during a routine upper endoscopy. It may help researchers understand esophageal lining injury and how well it recovers over time.
Nashville, TennesseeAges 18–99 - NCT05570448Recruiting
Endoscopy treatment using APC for chronic reflux disease
This trial studies whether an endoscopy procedure using APC (a type of heat/energy treatment) can improve symptoms in people with chronic GERD and confirmed acid reflux. It may help reduce reflux-related discomfort for people who meet specific testing and safety requirements.
Kansas City, MissouriAges 18–80 - NCT03669874Recruiting
Endoscopic surgery for long-term reflux using a special system
This trial tests whether an endoscopic fundoplication procedure (a reflux surgery done through the scope) using the MUSE system can better control long-term reflux symptoms. It likely fits people with chronic reflux confirmed by testing who may be candidates for surgical treatment.
MilanAges 18–70 - NCT04494048Recruiting
Registry for people considering endoscopic weight-loss procedures
This study keeps a record of people who are planning or recently had an endoscopic (camera-based) weight-loss procedure. The goal is to learn how these procedures work in real life and help doctors improve care.
New York, New YorkAges 18–89 - NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+ - NCT06280664Recruiting
Closing the hiatal gap for GERD relief
This trial tests if surgically closing a small hiatal defect helps reduce acid reflux (GERD) symptoms. It is for people who are surgical candidates and have confirmed acid exposure on testing.
Chicago, IllinoisAges 18–50 - NCT07158008Recruiting
Weight loss surgery for people with obesity and heartburn
This study compares two weight-loss surgeries for people who have both obesity and severe heartburn or GERD. One surgery combines part of the stomach removal with an anti-reflux wrap, while the other reroutes the stomach to help with weight loss and reflux.
KrakowAges 18–65 - NCT07634614Enrolling by invitation
Speech therapy for reflux-related bloating and belching
This trial tests whether speech and language therapy can help reduce bloating, belching, and other air-related symptoms in people with acid reflux (GERD). Researchers will measure how much the therapy improves these symptoms before and after treatment.
Schlieren, Canton of ZurichAges 18 years+ - NCT07711912Enrolling by invitation
Polish AntiReflux Study (POLAR)
This study looks at how well acid reflux surgery works for people with GERD (chronic heartburn). If you're already scheduled for this surgery at a participating hospital, you may be able to join.
Olsztyn, Warminsko-mazusrkieAges 18 years+ - NCT07148492Recruiting
Stitch to prevent reflux after gastric bypass
This trial tests adding an antireflux stitch to a type of gastric bypass surgery to see if it helps reduce acid reflux. It may help patients who are already scheduled for this surgery.
Peshawar, KhyberpukhtunkhwaAges Any age - NCT04994665Recruiting
Test of fixing the stomach to reduce reflux after sleeve surgery
This study checks whether a surgical “fix” (omentumpexy) can reduce acid reflux after sleeve gastrectomy. It’s mainly for adults having sleeve surgery who have a higher-risk body weight and related health problems.
BayonneAges 18 years+
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Common questions
- Are there clinical trials for gastro esophageal reflux?
- Yes. Clin2 currently lists 24 recruiting gastro esophageal reflux studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastro esophageal reflux trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastro esophageal reflux trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.