New procedure vs. acid-reducing pills for GERD
Part of Digestive system clinical trials.
This study compares a new procedure called anti-reflux mucosal valvuloplasty (ARMV) to acid-reducing medicines (PPIs) for treating GERD. It may help people who have had reflux for a long time and need daily PPIs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You have a small hiatal hernia (stomach bulging into the chest) that is 2 cm or smaller.
- Your reflux symptoms come back when you stop taking acid-reducing medicines (PPIs).
- You have been taking a PPI daily for at least a year, or twice daily for at least 8 weeks.
- A test shows abnormal acid levels in your esophagus.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new endoscopic procedure called anti-reflux mucosal ablation therapy to reduce acid reflux in people who still have symptoms despite taking acid-reducing medication. The goal is to see if this treatment helps improve heartburn and related symptoms.
This trial is testing a device called RefluxStop™ that is implanted during keyhole surgery to treat acid reflux (GERD). The study will check how safe and effective the device is for people with long-term GERD, and it aims to help reduce heartburn and other reflux symptoms.
This trial studies whether an endoscopy procedure using APC (a type of heat/energy treatment) can improve symptoms in people with chronic GERD and confirmed acid reflux. It may help reduce reflux-related discomfort for people who meet specific testing and safety requirements.
This trial tests a new way to treat GERD (chronic acid reflux) using a tiny camera and a device that delivers a gentle heat treatment (argon plasma coagulation) to the area where the stomach meets the esophagus. It's compared to a 'sham' procedure (you won't know which you get) to see if it stops acid from backing up better than medicine alone.
This study tests a new endoscopic procedure to help people with severe acid reflux that hasn't improved with strong medications. The procedure tightens the valve between the stomach and esophagus to reduce acid backing up.
This trial tests a new procedure where fat cells are taken from your own body and injected into the lower esophagus to help treat acid reflux that hasn't been controlled by medication. The goal is to strengthen the valve that keeps stomach acid from backing up into the esophagus.
Hear when a new GERD trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.