New procedure vs. acid-reducing pills for GERD
Part of Digestive system clinical trials.
This study compares a new procedure called anti-reflux mucosal valvuloplasty (ARMV) to acid-reducing medicines (PPIs) for treating GERD. It may help people who have had reflux for a long time and need daily PPIs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You have a small hiatal hernia (stomach bulging into the chest) that is 2 cm or smaller.
- Your reflux symptoms come back when you stop taking acid-reducing medicines (PPIs).
- You have been taking a PPI daily for at least a year, or twice daily for at least 8 weeks.
- A test shows abnormal acid levels in your esophagus.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new procedure called anti-reflux mucosal ablation to see if it helps people with long-lasting heartburn and acid reflux. It might be an option if medications haven't fully controlled your symptoms.
This study will track how well the RefluxStop device works and its safety for treating acid reflux in a general hospital setting. It aims to help people with long-term GERD who have not found relief from other treatments.
This trial compares the Stretta procedure to standard “conservative” treatment for people with ongoing GERD symptoms despite taking acid pills (PPIs). It aims to see whether Stretta can better control reflux and possibly help people stop or reduce PPIs safely.
This trial studies whether an endoscopy procedure using APC (a type of heat/energy treatment) can improve symptoms in people with chronic GERD and confirmed acid reflux. It may help reduce reflux-related discomfort for people who meet specific testing and safety requirements.
This trial tests a new way to treat GERD (chronic acid reflux) using a tiny camera and a device that delivers a gentle heat treatment (argon plasma coagulation) to the area where the stomach meets the esophagus. It's compared to a 'sham' procedure (you won't know which you get) to see if it stops acid from backing up better than medicine alone.
This trial compares a new device called RefluxStop to a standard surgery (Nissen fundoplication) for treating long-term acid reflux. It aims to see which one works better at stopping heartburn and other symptoms.
Hear when a new GERD trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.