Study drug SX-682 with pembrolizumab for advanced lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests SX-682 plus pembrolizumab (an immunotherapy) to treat metastatic or recurrent non-small cell lung cancer (NSCLC). It aims to see how well the combination works and whether it can shrink or control the cancer in people whose tumors have enough PD-L1.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old.
- Your lung cancer is confirmed as NSCLC, and you do not have certain gene changes (EGFR, ALK, ROS1, or RET).
- Your tumor PD-L1 level is at least 1% on an approved test.
- Your cancer is metastatic (spread) or recurrent, or stage IIIC/IV that can’t be cured with surgery or radiation.
- You can provide tumor tissue from before treatment (archived sample) or agree to a biopsy, and you may need another biopsy while on treatment if it’s safe.
- Your physical function is fairly good (ECOG 0–1), and your blood counts and organ tests are high enough (platelets, neutrophils, hemoglobin, liver enzymes, kidney function).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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