Prednisone plus aspirin to improve IVF outcomes in thyroid antibodies
Part of Hormones & metabolism, Immune system & allergy clinical trials.
This trial studies whether prednisone (an anti-inflammatory steroid) plus aspirin can improve IVF success in people who have thyroid autoimmunity, shown by specific thyroid antibody blood tests. If you qualify, the study may help find a treatment approach that supports embryo implantation and pregnancy chances.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your blood tests show thyroid antibodies: TPOAb higher than 34 IU/ml and/or TgAb higher than 115 IU/ml
- You’re between 20 and 38 years old
- You have enough developing egg/embryo numbers for IVF (at least 5 follicles >14 mm on trigger day, or at least 5 eggs retrieved, and embryo quality for frozen transfer if applicable)
- Your uterine lining and pregnancy setup must meet the study rules (for example, endometrium thickness must be at least 6 mm)
- You must agree to take part by signing the study consent form (ICF) after understanding risks and benefits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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