Prednisone and aspirin for IVF in women with thyroid antibodies
Part of Hormones & metabolism, Immune system & allergy clinical trials.
This trial tests whether taking prednisone (a steroid) and aspirin (a blood thinner) before embryo transfer improves pregnancy rates in women with thyroid antibodies. If you have these antibodies and are doing IVF, this could help reduce inflammation and improve your chances.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have higher than normal thyroid antibodies (TPOAb > 34 or TgAb > 115).
- You are between 20 and 38 years old.
- You have had at least 5 mature follicles (about 14 mm) at trigger time, or at least 5 eggs retrieved.
- If doing frozen embryo transfer, you have at least 2 cleavage-stage embryos (one good quality) or at least 1 good blastocyst.
- You do not have certain conditions like overactive thyroid, uterine adhesions, or stomach ulcers.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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