Clin2
NCT05580796Possibly a fitRecruiting

TCR-T cell therapy for HLA-A*02 positive solid tumors

Solid Tumor

Part of Cancer clinical trials.

This trial tests a personalized immune-cell treatment made from your own blood to target certain solid tumors. You may be eligible if your tumor has a specific protein pattern and you have tried standard treatments without success.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
50 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You must be 18–70 years old and be able to sign consent and complete study visits and tests
  • You have a solid cancer that has not responded to standard treatments
  • Your body must have HLA-A*02, and your tumor must show the target protein strongly (2+ or 3+ in enough cells)
  • Any side effects from prior cancer treatments must be mostly gone (grade 0–1 or an acceptable level)
  • Your blood, liver, kidney, and clotting tests must be good enough for treatment
  • A tumor tissue sample must be available for target testing (archived sample or fresh biopsy; bone biopsy not accepted)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07570563Recruiting· Phase 1/Phase 2
T Cell Immunotherapy for Advanced Cancers

This study tests a new immunotherapy using specially engineered immune cells (called TCR-enhanced Vδ2 T cells) to treat blood cancers or solid tumors that haven't responded to standard treatments. The goal is to see if these cells can safely shrink tumors and improve survival.

Beijing, Beijing Municipality
NCT07342738Not yet recruiting· Early Phase 1
TCR-T cell therapy for advanced solid tumors with KRAS mutations

This trial tests a new type of immune cell therapy (TCR-T) designed to attack cancer cells with a specific KRAS mutation. It may be an option for people with advanced solid tumors who have run out of standard treatments.

Guangzhou, Guangdong
NCT07275853Not yet recruiting· Phase 1
Personalized TCR therapy for advanced solid tumors

This trial tests a personalized treatment that uses your own immune cells, modified to recognize and attack your cancer. It may help people with advanced solid tumors who have not improved with standard treatments.

Beijing
NCT06150365Recruiting· Early Phase 1
Personalized T-cell therapy for advanced solid tumors (KSX01-TCRT)

This study tests a personalized treatment made from your own immune cells (T cells) that are re-engineered to recognize and attack your specific tumor. It is for people with advanced solid tumors that have not responded to other treatments. If you qualify, you will have a blood draw and a tumor sample collected to create your own custom T cell therapy.

Beijing
NCT07859462Not yet recruiting· Phase 1
A new immune cell treatment for advanced solid tumors

This phase 1 trial tests a new way to use your own immune cells to fight advanced solid tumors. The treatment is given directly into the tumor. It is for people who have run out of standard treatment options.

Beijing, Beijing Municipality
NCT07266298Recruiting· Phase 1
T-cell therapy for advanced solid tumors

This trial tests a new therapy using your own immune cells, engineered to recognize and attack cancer cells. It is for people with advanced solid tumors who have no other standard treatment options.

Beijing, Beijing Municipality

Hear when a new Solid Tumor trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.