Progesterone vs another hormone added to estrogen for menopause symptoms
Part of Women’s health & pregnancy clinical trials.
This Phase 3 study compares two types of progesterone—micronized progesterone versus norethisterone acetate—both used with estrogen to treat menopause symptoms that affect daily life. It aims to see which combination works better and is tolerated over time for women with an intact uterus.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re a woman age 45 to 60 and have been through menopause for at least 1 year
- You have menopause symptoms like hot flushes/sweating and/or sleep problems that lower your quality of life
- Your weight is within a BMI range of over 19 and up to 32
- You still have your uterus (no uterus removal surgery)
- You can’t have had certain hormone treatments recently—if you used menopause hormone therapy, there must be a washout period before screening
- You can’t have certain serious risks or conditions, especially related to breast cancer, womb (endometrial) cancer, unexplained bleeding, or major heart/stroke risk
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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