Testing vactosertib for osteosarcoma that keeps coming back
Part of Cancer clinical trials.
This Phase 1/2 study tests how safe and how well vactosertib works for adolescents and adults with osteosarcoma that has returned, stopped responding, or is getting worse despite prior treatment. You may be able to join if you meet age, cancer, recovery-from-prior-therapy, and health-test requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 12 years old (no younger children)
- Have osteosarcoma confirmed by biopsy (tissue sample)
- Have measurable cancer on scans and evidence it has progressed or relapsed after standard therapy
- Have mostly recovered from prior chemo/immunotherapy side effects (leftover issues must be mild, except hair loss, low appetite, and pain)
- Have adequate bone marrow, kidney, liver, and heart health based on blood tests and heart scans
- Be able to swallow tablets and agree to consent/assent paperwork
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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