Apatinib with chemo for advanced osteosarcoma
Treatments studied
Part of Cancer clinical trials.
This study tests whether the combination of two drugs, apatinib (a targeted therapy) and liposomal irinotecan (a chemotherapy), can help people with osteosarcoma that has not responded to standard treatments or has spread. The goal is to see if the combination can shrink tumors or slow the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have osteosarcoma that has continued to grow or come back after at least two standard treatments.
- You have at least one tumor that can be measured on a scan (like a CT or MRI).
- You are physically able to do most daily activities (ECOG score 0 or 1) and expected to live at least 3 months.
- You have not been treated with apatinib or irinotecan (or similar drugs) before.
- Any side effects from prior treatments (except hair loss) have resolved or are mild.
- Your major organs (like kidneys, liver, and bone marrow) are working well enough, as shown by blood tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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