Targeted drugs plus chemo for advanced osteosarcoma
Treatments studied
Part of Cancer clinical trials.
This trial combines four targeted drugs (gefitinib, trametinib, disulfiram, sunitinib) with standard chemotherapy to treat osteosarcoma that has spread or come back. The goal is to see if this drug mix helps shrink tumors or keep them from growing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 6 and 49 years old.
- You have osteosarcoma that is either newly diagnosed and has spread to other parts of the body, or has come back after previous treatment.
- You are able to swallow pills whole or have a liquid version available.
- Your blood counts, kidney, liver, and heart function are within safe limits (your doctor can check this).
- You are willing to have a small tumor sample taken before starting treatment and again during surgery (for research).
- You agree to use effective birth control during treatment and for 12 months after stopping, if there is any chance of pregnancy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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