High-dose buprenorphine start in the emergency department for fentanyl use
Part of Mental health clinical trials.
This Phase 3 study tests whether starting a high dose of buprenorphine in the emergency department helps people with opioid use disorder come through withdrawal more safely and effectively. It focuses on people whose urine test shows fentanyl and who are already in withdrawal when they arrive.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can sign and date informed consent after being told about the study
- You are being seen in the emergency department during the screening hours
- You meet diagnostic criteria for moderate to severe opioid use disorder
- You are in active withdrawal (COWS score of 8 or higher)
- Your urine drug test is positive for fentanyl
- You can speak English or Spanish enough to understand study steps
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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