Clin2
NCT06726200Likely a fitRecruiting

Comparing buprenorphine formulations for fentanyl addiction

Opioid Use Disorder

Treatments studied

Part of Mental health clinical trials.

This study tests two different forms of buprenorphine (a medication for opioid addiction) to see which works better for people who use fentanyl or other strong synthetic opioids. If you are seeking treatment for opioid use, this trial may help you find the most effective option.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
60 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are 18 to 65 years old and want treatment for opioid addiction.
  • You have been using fentanyl or other strong synthetic opioids regularly.
  • You have not taken buprenorphine or methadone in the past month.
  • You are not pregnant, breastfeeding, or planning pregnancy, and you are willing to use birth control if needed.
  • You do not have a serious untreated medical or mental health condition that could make the study unsafe.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06379984Recruiting· Phase 2
Quick-start buprenorphine for opioid addiction with fentanyl use

This trial tests a way to quickly start buprenorphine (a medication for opioid addiction) in an outpatient clinic for people who use fentanyl. It aims to make starting treatment easier and faster, without needing to go through full withdrawal first.

Philadelphia, Pennsylvania
NCT05589181Recruiting· Phase 3
High-dose buprenorphine start in the emergency department for fentanyl use

This Phase 3 study tests whether starting a high dose of buprenorphine in the emergency department helps people with opioid use disorder come through withdrawal more safely and effectively. It focuses on people whose urine test shows fentanyl and who are already in withdrawal when they arrive.

Newark, New Jersey
NCT05450718Recruiting· Phase 4
Low-dose buprenorphine start for opioid use disorder

This trial tests whether starting buprenorphine using a low-dose plan is a safe and workable way to treat opioid use disorder. You may be able to join if you are 18+, have opioid use disorder, and can follow the study medication and visits.

The Bronx, New York
NCT07469501Not yet recruiting· Phase 4
Comparing low-dose vs. direct-inject buprenorphine for fentanyl users

This study compares two ways to start buprenorphine (a medicine for opioid use disorder) for people who use fentanyl daily. One group gets a low starting dose, the other gets a direct injection. The goal is to see which approach helps people stay in treatment longer.

San Francisco, California
NCT06316830Recruiting· Phase 2/Phase 3
Finding the best buprenorphine dose for opioid use disorder

This trial tests different doses of buprenorphine to find the safest and most effective one for treating opioid use disorder and preventing overdose. It is for people who have used fentanyl and are starting or continuing buprenorphine treatment.

Providence, Rhode Island
NCT06323824Recruiting· Phase 4
Methadone vs. buprenorphine for opioid use disorder treatment

This study compares two medications, methadone and buprenorphine, to see which helps people stay in treatment for opioid use disorder. You may be eligible if you are starting a new treatment episode.

Oakland, California

Hear when a new Opioid Use Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.