Clin2
NCT05450718Possibly a fitRecruiting

Low-dose buprenorphine start for opioid use disorder

Opioid Use Disorder

Treatments studied

Part of Mental health clinical trials.

This trial tests whether starting buprenorphine using a low-dose plan is a safe and workable way to treat opioid use disorder. You may be able to join if you are 18+, have opioid use disorder, and can follow the study medication and visits.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
70 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are at least 18 years old and can sign the consent form
  • You have opioid use disorder (doctor-confirmed) and can take medicine under the tongue
  • You agree to follow the study’s exact buprenorphine start schedule and attend visits
  • You speak English or Spanish
  • If you could become pregnant, you agree to use highly effective birth control during the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06316830Recruiting· Phase 2/Phase 3
Finding the best buprenorphine dose for opioid use disorder

This trial tests different doses of buprenorphine to find the safest and most effective one for treating opioid use disorder and preventing overdose. It is for people who have used fentanyl and are starting or continuing buprenorphine treatment.

Providence, Rhode Island
NCT06379984Recruiting· Phase 2
Quick-start buprenorphine for opioid addiction with fentanyl use

This trial tests a way to quickly start buprenorphine (a medication for opioid addiction) in an outpatient clinic for people who use fentanyl. It aims to make starting treatment easier and faster, without needing to go through full withdrawal first.

Philadelphia, Pennsylvania
NCT05589181Recruiting· Phase 3
High-dose buprenorphine start in the emergency department for fentanyl use

This Phase 3 study tests whether starting a high dose of buprenorphine in the emergency department helps people with opioid use disorder come through withdrawal more safely and effectively. It focuses on people whose urine test shows fentanyl and who are already in withdrawal when they arrive.

Newark, New Jersey
NCT06726200Recruiting· Early Phase 1
Comparing buprenorphine formulations for fentanyl addiction

This study tests two different forms of buprenorphine (a medication for opioid addiction) to see which works better for people who use fentanyl or other strong synthetic opioids. If you are seeking treatment for opioid use, this trial may help you find the most effective option.

New York, New York
NCT07176351Not yet recruiting· Phase 4
Mobile clinic study of extended-release buprenorphine for opioid use disorder

This trial tests a long-acting, once-monthly injection of buprenorphine (BRIXADI) given from a mobile pharmacy clinic. It aims to see if this approach is acceptable and practical for people with opioid use disorder, making treatment more accessible.

New Haven, Connecticut
NCT07439549Recruiting· Phase 4
Quick-start buprenorphine with naloxone for opioid use disorder

This study tests a faster way to start buprenorphine (a medication for opioid use disorder) by using naloxone to briefly trigger mild withdrawal. This could help people get started on treatment more comfortably and quickly.

Vancouver, British Columbia

Hear when a new Opioid Use Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.