Clin2
NCT05598112Worth exploringRecruiting

Oral stool-based microbiome treatment for healthy aging

AgingFrailty

Treatments studied

Part of Digestive system, Hormones & metabolism clinical trials.

This early-stage study tests whether changing the gut bacteria using an oral stool-based treatment (called oral FMT) can improve health in older adults. It aims to see if this approach affects aging-related changes, including gut and body function.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
210 people
Ages
70 years to 85 years
Study type
Interventional

Who can take part

  • You are between 70 and 85 years old.
  • You can understand the study and sign consent after the team explains it.
  • You have not taken antibiotics or probiotics in the last 4 weeks.
  • You do not have major severe liver or kidney problems (including kidney failure needing dialysis).
  • You do not have certain recent serious heart or brain events (like stroke or heart attack in the past 6–12 months).
  • You do not have dementia or certain brain/mental health conditions, and you can communicate and care for yourself.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07454616Recruiting
Supplement and exercise study for pre-frail adults

This study tests whether a special nutrient supplement combined with a simple exercise routine can improve health markers linked to living longer. It is designed for adults who are starting to feel less strong or energetic but are not yet frail.

Singapore
NCT07386795Not yet recruiting
Gut bacteria transplant with prebiotics for chronic constipation

This study tests whether transplanting healthy gut bacteria (microbiota) combined with prebiotics can help people with long-term constipation that hasn't gotten better with standard treatments. It may offer a new option for those who have tried laxatives and other therapies without relief.

Beijing
NCT07628777Not yet recruiting· Phase 1/Phase 2
Gut Bacteria Transplant for Heart Failure in Older Adults

This study tests whether transplanting healthy gut bacteria can help older adults with heart failure that has a preserved ejection fraction (HFpEF). Researchers think the gut microbiome may play a role in heart function and hope this treatment could improve symptoms and quality of life.

Xi’an, Shanxi
NCT03995342Enrolling by invitation
Study gut bacteria and frailty in older adults

This study looks at whether gut bacteria (intestinal flora) are linked to frailty in people age 65 and older. It will also test an intervention to see if changing gut bacteria can help reduce frailty.

Xi'an, Shaanxi
NCT07407894Recruiting
Probiotic study for healthy aging in midlife adults

This trial tests a probiotic supplement called iVS-1 to see if it can slow biological aging in healthy adults aged 40-75. Researchers want to learn if this probiotic may help support health as you age.

New Port Richey, Florida
NCT07033637Not yet recruiting
Probiotics and healthy aging: a gut health study

This study tests whether taking probiotics can improve gut health and overall wellness in older adults. It is looking for people aged 60 and older who are already active in a physical activity program.

Hear when a new Frailty trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.