Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04518423Recruiting
Study frailty and fitness changes in older adults living at home
This study looks at how “frailty” (lower strength and resilience) and “pre-frailty” change over time in older adults who live at home. It may help researchers understand what factors affect aging and strength, so future care can start earlier.
OpoleAges 65 years+ - NCT07815392Recruiting
Frailty and recovery after gastrointestinal cancer surgery
This study looks at how frailty, or overall physical weakness, affects recovery after surgery for gastrointestinal cancer in people aged 60 and older. The findings may help doctors better prepare patients for surgery and improve their recovery.
Van, VanAges 60 years+ - NCT05738252Recruiting
Frailty tests to assess surgical risk in gynecologic cancers
This trial studies simple “frailty” assessments (tests of strength, memory, and daily functioning) to better predict risk in people with gynecologic cancers who are planning or having surgery. If you qualify, the results may help doctors identify who needs extra support before and after surgery.
Hamilton, OntarioAges 55–110 - NCT06955975Recruiting
Pectin supplement for frailty in older adults
This study tests if daily pectin, a fiber found in fruits, can improve strength and health in older adults who are frail or pre-frail. It compares pectin to a placebo over time.
Nottingham, NottinghamAges 65 years+ - NCT06889545Recruiting
Comparing ways to measure frailty before surgery in older adults
This trial compares different ways to measure frailty in people aged 70+ before surgery lasting at least 2 hours, to see which tool works best.
HamburgAges 70 years+ - NCT06393647Recruiting
Blood markers and frailty in older cancer surgery patients
This study looks at how certain blood markers (albumin/creatine ratio, vitamin B12, and folate) relate to frailty in older adults having surgery for stomach or intestinal cancer. The goal is to understand if these markers can help predict which patients may be more frail.
Çankaya, AnkaraAges 65–90 - NCT05257226Recruiting
Study of outcomes by frailty in surgical patients
This trial looks at whether “frailty” (how weak or vulnerable someone is) changes short- and long-term outcomes after surgery. It may help doctors better predict who could benefit from extra support before and after surgery.
KochiAges 18–90 - NCT07824700Recruiting
Prehabilitation for frail patients before heart surgery
This program helps mildly or moderately frail patients get physically stronger before their heart surgery or procedure. It is designed to improve recovery and outcomes by starting exercises and support during the waiting period.
Hong KongAges 18 years+ - NCT07634406Recruiting
Phone-based frailty support program for older adults
This study tests whether nurses can help older adults stay strong and independent through regular phone calls and guidance. You'll receive support from a nurse over the telephone to manage weakness and prevent health decline.
Simav, KütahyaAges 65 years+ - NCT07452263Recruiting
Frailty screening tool for older adults before major surgery
This study tests a simple frailty screening tool in older adults before major surgery. It aims to see if the tool helps identify patients who might need extra support before and after their operation.
Reykjavik, HofudborgarsvaedidAges 70 years+ - NCT07442656Recruiting
Frailty and outcomes in older adults with pneumonia
This study looks at how frailty (overall weakness and decline) affects recovery in older adults who come to the emergency room with pneumonia. The goal is to understand what outcomes patients can expect based on their frailty level.
Izmir, BornovaAges 65 years+ - NCT07367828Recruiting
Frailty screening for older adults before surgery
This study tests how well simple frailty screening tools predict recovery and complications after major surgery in people aged 70 and older. The goal is to help doctors and patients better understand surgical risks.
Reykjavik, HofudborgarsvaedidAges 70 years+ - NCT07181096Recruiting
Frailty in kidney transplant patients and kidney function
This study looks at frailty (weakness and tiredness) in kidney transplant patients and how it relates to how well the transplanted kidney is working. It may help find ways to improve long-term transplant health.
AlexandriaAges 18 years+ - NCT07030179Recruiting
Frailty, kidney injury, and blood pressure in non-cardiac surgery
This study looks at whether a patient's level of frailty (overall weakness and health before surgery) affects their risk of acute kidney injury after non-cardiac surgery, and whether blood pressure changes during surgery play a role in that link.
Nanjing, JiangsuAges 18 years+ - NCT06324149Recruiting
Frailty and aging conditions in chronic diseases
This study looks at how frailty affects the course of chronic diseases and how chronic diseases affect frailty. It may help understand aging-related conditions better.
MilanAges 18–100 - NCT06870149Recruiting
Dance program to improve mobility in older adults at risk
This study tests whether a structured dance program (called GERAS DANCE) can help older adults who are frail or at risk of losing mobility. You would attend dance sessions at the YMCA twice a week, and researchers will see if it improves your walking and daily function.
Hamilton, OntarioAges 65–100 - NCT05893342Recruiting
Checking frailty during surgery in older adults
This study looks at “frailty,” or how well the body may handle stress, around the time of surgery in people age 65 and older. It may help doctors better understand who is at higher risk and how to plan care around surgery.
Las Palmas de Gran Canaria, Las PalmasAges 65 years+ - NCT04717869Recruiting
Studying frailty support for ICU patients
This trial looks at ways to help “frailty” (low strength and resilience) in people staying in intensive care units. It mainly enrolls adults who expect to be in the ICU for more than 24 hours, and it tries to avoid people whose mobility problems have other causes.
Los Angeles, CaliforniaAges 18 years+ - NCT07848802Recruiting
Physical function and fall risk in older adults
This study looks at how a program for older adults affects physical function and the risk of falling. It involves assessments to see if the program helps keep you steady and active.
Lalín, PontevedraAges 70 years+ - NCT07845656Recruiting
Home exercise program for weak muscles and bones in older adults
This study tests a home exercise program designed for older adults with both weak muscles and weak bones who also feel frail. The program uses a smartphone to guide your exercises, aiming to make you stronger and more steady in your daily life.
Nantong, JiangsuAges 60–85 - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+ - NCT04524247Recruiting
Testing a custom stent graft for frail aortic aneurysms
This study looks at a specialized, customized stent graft to treat certain aneurysms (bulges) of the aorta in people who may be considered frail. It’s meant to see how well the device works and how safely it can be used in patients who fit specific aneurysm patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT06267378Recruiting
Frailty and its effects on older patients having major gut surgery
This study looks at how frailty affects recovery and outcomes for patients aged 70 and older who are having planned surgery to remove colorectal cancer. The goal is to better understand frailty's impact so care can be improved.
Doncaster, South YorkshireAges 18 years+ - NCT07813702Recruiting
Urinary leakage and aging-related health problems
This study looks at how urinary leakage relates to other common health issues in older adults. It may help doctors better understand and manage these problems together.
Karabük, MerkezAges 65 years+
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Frailty trials by city
Studies with a site in or near these metro areas.
Frailty trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 245 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.