Clin2
NCT05598528Possibly a fitRecruiting

Study why some lung cancers don’t respond to EGFR pills

Lung Cancer, Non-small CellEGFR Gene MutationEGFR-TKI Resistant MutationPrimary ResistanceCirculating Tumor DNA

Part of Cancer, Lungs & breathing clinical trials.

This study looks at why certain EGFR-positive advanced lung cancers resist third-generation EGFR tablet treatment given as the first treatment. Your body samples and scan results help researchers understand the resistance, which may guide better future care.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
210 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are older than 18 years
  • You have non-small cell lung cancer (NSCLC) that can’t be fully removed or has spread
  • You have at least one tumor spot that can be measured on scans
  • Your tumor test shows an EGFR mutation (from tissue or fluid such as pleural fluid or spinal fluid)
  • You plan to start third-generation EGFR tablets as your first treatment
  • You can share medical records, imaging, and provide samples, and you agree to sign consent

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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