Clin2
NCT06323148Possibly a fitNot yet recruiting

Personalized treatment based on tumor DNA test after lung cancer surgery

Lung CancerEGFR Gene MutationMinimal Residual Disease

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This study tests whether using a blood test to detect leftover tumor DNA after surgery can guide extra treatment for people with EGFR-mutant lung cancer. The goal is to see if starting or avoiding targeted therapy based on this test improves outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
226 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older.
  • You must have non-small cell lung cancer that has been surgically removed (stage II to IIIA).
  • Your cancer must have a specific EGFR gene change (19del or 21L858R).
  • You must have had a complete resection (no tumor left behind, R0).
  • You must not have had any chemotherapy, radiation, targeted therapy, or immunotherapy before surgery.
  • Your overall health must be good, and your blood counts and organ function must be within certain limits.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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