Adjuvant targeted therapy guided by ctDNA in EGFR-mutant lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests whether using a blood test (ctDNA) to guide targeted therapy after surgery can improve outcomes for patients with stage II-IIIA non-small cell lung cancer that has an EGFR mutation. If you qualify, you may receive a targeted pill (osimertinib) based on your ctDNA results.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with stage II, IIIA, or stage IIIA (N1-N2) non-small cell lung cancer.
- Your cancer has a specific EGFR mutation (19del or 21L858R).
- You are able to have surgery to completely remove the tumor (R0 resection).
- You have good overall health (ECOG score 0-1) and adequate blood counts and organ function.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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