Breast cancer surgery with a tumor-bed boost and standard radiation
Part of Cancer, Skin clinical trials.
This study looks at whether adding extra targeted radiation to the tumor area before breast-conserving surgery, then using modern breast surgery techniques and whole-breast radiation afterward, improves outcomes for early-stage breast cancer. You may be offered a treatment plan designed to better treat the area where the tumor was removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with invasive breast cancer (not just pre-cancer).
- Your cancer is early stage in the armpit: no spread to lymph nodes on exam/imaging or biopsy.
- Your planned treatment is breast-conserving surgery (not a full mastectomy).
- You do not have cancer that has spread to distant organs, and the tumor is more than 5 mm from the skin with no rib or muscle involvement.
- You have not had chemotherapy or other treatment before surgery, and you can get an MRI.
- You can safely have study procedures: no serious uncontrolled heart disease, recent heart attack or stroke, uncontrolled diabetes, active infection, or certain other active illnesses; you must also have blood tests that meet lab thresholds and be able to follow up.
- If you could become pregnant, you must use reliable birth control, and you must be willing to sign consent and attend follow-up.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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