Methimazole for progressive glioblastoma after planned surgery
Treatments studied
Part of Cancer clinical trials.
This Phase 2 trial studies whether methimazole, a medicine that affects the thyroid system, can help control progressive glioblastoma (a fast-growing brain tumor) after surgery. It looks at safety and how well the treatment works when given after your surgical plan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed grade 4 glioma (or related grade 4 astrocytoma) and your doctors plan surgery to remove tumor tissue.
- You are at least 18 years old and can take whole tablets by mouth.
- You have enough “body reserves” for treatment (blood counts and liver/kidney tests are within required limits).
- Your thyroid tests must be normal, and you have no history of hyperthyroidism or hypothyroidism.
- You must not have taken methimazole for this glioblastoma before.
- If you can get pregnant, you must have a negative pregnancy test and use effective birth control; you also cannot be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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