Troriluzole before surgery for recurrent glioblastoma
Part of Brain & nervous system, Cancer clinical trials.
This trial tests whether an investigational drug called troriluzole can help people with recurrent glioblastoma (a type of brain tumor). You would take the drug for a short time before your planned surgery, so researchers can study how the drug affects your tumor tissue. The goal is to see if it might slow tumor growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with a glioblastoma that is IDH-wildtype (a specific genetic type)
- Your tumor has come back after previous treatment with radiation and possibly chemotherapy, and you have had no more than 2 relapses
- You are able and willing to have surgery to remove the tumor, and part of the tumor is near the surface of the brain (gray matter)
- You are generally in good health (Karnofsky score 60 or higher) and your blood counts and organ function are within study limits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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