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NCT07604285Possibly a fitNot yet recruiting

New drug safety with radiation and chemo for newly diagnosed glioblastoma

Glioblastoma

Part of Cancer clinical trials.

This study tests a new medicine (MT-125) combined with standard radiation and chemotherapy for people with newly diagnosed glioblastoma that has a specific gene change (MGMT methylated). The goal is to see if it is safe and tolerable, and to look for early signs it might help.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
36 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be at least 18 years old.
  • You must have a new brain cancer called glioblastoma that has not been treated yet, and your tumor must have the MGMT methylated feature.
  • You should be able to take care of yourself (fully active or able to do light activities) — your doctor will check this.
  • Your heart, liver, and kidney function must be within acceptable limits — your doctor will test this.
  • If you are taking steroids for brain swelling, the dose must have been stable for at least 2 weeks before starting the study.
  • You must agree to use effective birth control if you or your partner could become pregnant, and you must not be pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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