New treatment for newly diagnosed transplant-ineligible myeloma
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This Phase 3 study compares a three-drug combination (elranatamab, daratumumab, and lenalidomide) versus a standard three-drug treatment (daratumumab, bortezomib, lenalidomide, plus dexamethasone). It aims to see which plan works better for people newly diagnosed with multiple myeloma who cannot get a stem cell transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with multiple myeloma.
- You have measurable myeloma activity on blood or urine tests.
- You are not a good candidate for a stem cell transplant (often due to age and/or other health problems).
- Your health and daily function are fairly good (ECOG 0–2).
- You are not pregnant and can use reliable birth control during the study.
- You do not have certain other myeloma-related conditions (like smoldering myeloma or plasma cell leukemia).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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