Test ONC201 to prevent colorectal polyp return in high-risk people
Part of Cancer, Digestive system, Genetic & congenital clinical trials.
This Phase 1 study tests whether ONC201 is safe and may help prevent colorectal polyps (adenomas) from coming back. You’d also undergo planned colon/rectum camera exams to check for new or changing polyps.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older
- You are high risk for colorectal adenomas (for example, FAP and/or many adenomas on a recent colonoscopy)
- Your planned colonoscopy (standard care) must show at least two adenomatous polyps 5 mm or larger
- You must have enough blood counts and normal liver and kidney test results for the study
- You must be able to do a second procedure about 12 weeks after starting ONC201
- If you can become pregnant, you must use reliable birth control during the study and for 4 weeks after stopping
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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