Studying polyp growth in familial adenomatous polyposis
Part of Cancer, Digestive system, Genetic & congenital clinical trials.
This study tracks how colorectal polyps develop in people with familial adenomatous polyposis (FAP), a genetic condition that causes many polyps. It aims to better understand and possibly prevent cancer, without immediate surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 40 years old.
- You have between 100 and 1,000 polyps in your colon.
- Polyps are confirmed to be adenomas (non-cancerous growths).
- You have a specific change (mutation) in the APC gene.
- You have no cancer or spread of cancer, and you have not had colon surgery before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a tailored plan for surveillance (check-ups) and interventions to find and remove new growths early in people with familial adenomatous polyposis (FAP) after bowel surgery. It may help lower the chance of cancer by closely monitoring and treating polyps when they appear.
This early-phase trial studies REC-4881 in adults with familial adenomatous polyposis (FAP), a condition that causes many colon/rectum and duodenal polyps. It aims to see whether the treatment can safely help control or shrink polyp growth in people who have had bowel surgery.
This trial tests a personalized plan for regularly checking and treating stomach and first-part of intestine polyps in people with familial adenomatous polyposis (FAP). It may help by catching problems early and choosing the right intervention at the right time.
This study looks at how bacteria and your environment might affect polyp growth in people with familial adenomatous polyposis (FAP) after colon removal. By collecting stool samples and medical information, researchers hope to find ways to reduce polyp risk.
This trial tests a new drug, TPST-1495, to reduce the number of benign polyps in the small intestine for people with a condition called familial adenomatous polyposis (FAP). If you join, you will likely not know if you receive the drug or a placebo, to see if the drug is helpful.
This study reviews duodenal polyps in people with FAP to improve how they are classified. It uses existing medical records from endoscopies (scope tests) to help doctors better understand and manage polyp growth.
Hear when a new Familial Adenomatous Polyposis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.