Test of ZB002 safety and dosing in rheumatoid arthritis
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This early-phase study tests whether ZB002 is safe in people, and how the body handles the drug. It includes both healthy volunteers and people with rheumatoid arthritis (RA) to see if the drug has a predictable blood level pattern.
Summary written for real people, not researchers, by Clin2.
Who can take part
- If you’re in the RA group: you must be diagnosed with rheumatoid arthritis for at least 3 months.
- If you’re in the RA group: you must take stable methotrexate weekly (7.5–25 mg) for at least 3 months before starting.
- You must be within the age and body-size limits (RA group: 18–70; BMI usually 18–40).
- You must be able to provide informed consent and follow study instructions.
- You cannot have certain infections (including HIV, hepatitis B or C, or active tuberculosis).
- You should avoid major recent medication changes or recent investigational drugs before dosing.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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