Testing a new drug for rheumatoid arthritis
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This trial tests a new medication (BMS-986454) for people with rheumatoid arthritis who haven't responded well enough to methotrexate. It aims to see if the drug is safe and how it works in the body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old when your rheumatoid arthritis started.
- You must have been diagnosed with rheumatoid arthritis based on standard medical criteria (ACR/EULAR 2010).
- You must have swelling in at least one hand or wrist joint at the screening visit and the day before the study starts.
- You must have tried methotrexate but it didn't work well enough (incomplete responder).
- You cannot have any other serious medical condition (like heart, lung, kidney, or liver problems) that would make the study risky for you, as decided by the study doctor.
- You must not have severe rheumatoid arthritis as measured by a special score (DAS28-CRP) at screening or the day before the study starts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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