Clin2
NCT07433335Possibly a fitRecruiting

First study of sr-878 for rheumatoid arthritis safety

Rheumatoid Arthritis

Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.

This study tests a new investigational drug called SR-878 for people with rheumatoid arthritis. It aims to see if the drug is safe and tolerable. You may join if you are between 18 and 60, have RA for at least 3 months, and take a stable dose of methotrexate.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
27 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You are between 18 and 60 years old.
  • You have been diagnosed with rheumatoid arthritis for at least 3 months.
  • You are on a stable dose of methotrexate for at least 4 weeks.
  • You can stay in the hospital for about 3 days as part of the study.
  • You are not pregnant, breastfeeding, or planning to become pregnant; you use highly effective birth control if needed.
  • You do not have other serious health conditions or active infections like HIV, hepatitis, or tuberculosis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07171983Recruiting· Phase 1
Testing a new drug for rheumatoid arthritis

This trial tests a new medication (BMS-986454) for people with rheumatoid arthritis who haven't responded well enough to methotrexate. It aims to see if the drug is safe and how it works in the body.

Hyderabad, Andhra Pradesh
NCT06857227Recruiting· Phase 1
Study of GNC-038 for active rheumatoid arthritis

This trial tests a new experimental antibody called GNC-038 for people with moderate to severe rheumatoid arthritis (RA) that hasn't responded well enough to standard treatments. It aims to see if targeting specific immune cells can reduce inflammation and improve symptoms.

Shanghai, Shanghai Municipality
NCT07137598Recruiting· Phase 2
A study of RO7790121 for moderate to severe rheumatoid arthritis

This study tests a new drug, RO7790121, for people with rheumatoid arthritis (RA) who have not gotten better with or could not tolerate common treatments like TNF inhibitors or JAK inhibitors. It aims to see if the drug is safe and can help reduce joint pain and swelling.

Peoria, Arizona
NCT03828344Not yet recruiting· Phase 1
Safety of a single intravenous treatment for hard-to-treat rheumatoid arthritis

This trial tests a new one-time IV treatment (BX-U001) for people with rheumatoid arthritis that hasn't improved with standard therapies. The goal is to check its safety and how well people tolerate it.

NCT06590090Not yet recruiting· Phase 2
Testing a new treatment for rheumatoid arthritis

This study tests whether a new investigational drug called Natrunix, when combined with your usual methotrexate, can improve symptoms of moderate to severe rheumatoid arthritis. The goal is to reduce joint pain and swelling and help you feel better.

NCT06201416Recruiting· Phase 1
Single dose of SBT777101 for rheumatoid arthritis

This study tests a single dose of an experimental drug called SBT777101 for people with moderate to severe rheumatoid arthritis who have already tried and failed at least two advanced treatments. The goal is to see if it is safe and how the body handles it.

Scottsdale, Arizona

Hear when a new Rheumatoid arthritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.