Clin2
NCT05662111Possibly a fitRecruiting

Etidronate treatment for brain calcifications in Fahr disease

Fahr DiseaseFahr SyndromePrimary Familial Brain Calcification

Part of Brain & nervous system, Genetic & congenital clinical trials.

This Phase 2 study tests whether etidronate (a medicine that affects bone-calcium handling) can help people with Fahr disease or a similar condition marked by calcium deposits in the brain. It will also check safety and whether certain tests can track changes over time.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
98 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older.
  • You have been diagnosed (or are being diagnosed) with Fahr disease or syndrome based on symptoms and a brain CT scan showing abnormal calcifications.
  • Your head CT shows calcifications in specific brain areas, and the amount is higher than what’s expected for your age.
  • You can take the study medicine by mouth and your esophagus works well enough to swallow it.
  • Your calcium and vitamin D blood tests are not too low (they can be corrected first).
  • You have no major kidney problems and you have no allergy to etidronate.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05832580Recruiting· Phase 3
Preventing calcium buildup in skin, eyes, and blood vessels

This Phase 3 study tests a medicine to help prevent abnormal calcium (called ectopic mineralization) from building up in people with pseudoxanthoma elasticum (PXE). It aims to slow or reduce new damage over time.

Utrecht
NCT05776212Recruiting
Imaging study for certain heart amyloidosis types and heart thickening

This trial uses special heart imaging to better measure how amyloid deposits affect the heart in people with certain diagnoses. The goal is to understand which imaging signals match your disease and to see if this approach could help guide care.

Groningen
NCT04010201Recruiting
Study of brain calcium deposits on CT scans

This study looks at people who have extra calcium deposits in the brain seen on a CT scan (and also includes some relatives and healthy volunteers). It aims to better understand who has brain calcification and what it may mean, using research visits and scan-based measurements.

Fuzhou, Fujian
NCT05336695Recruiting· Phase 1/Phase 2
Brain scan study to measure fibrin in Alzheimer’s

This early study (Phase 1/2) uses brain imaging to look for “fibrin” (a blood-clot–related protein) in people with Alzheimer’s disease and related conditions. The goal is to understand whether fibrin changes can be seen on scans and what it might mean for Alzheimer’s.

Boston, Massachusetts
NCT07470710Not yet recruiting· Early Phase 1
New brain scan for neurodegenerative diseases

This trial studies a new imaging agent that helps doctors see brain changes related to Alzheimer's, Parkinson's, and similar conditions. The goal is to improve diagnosis and monitoring of these diseases.

NCT03143374Recruiting· Phase 2/Phase 3
Brain scan study for tau in neurodegenerative diseases

This study uses a special PET/CT brain scan to look at a protein called tau in people with memory/thinking and movement disorders. The results may help researchers understand how these diseases affect the brain and improve future diagnosis or care.

Philadelphia, Pennsylvania

Hear when a new Fahr Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.