Stem cells injected in brain for mild to moderate Alzheimer’s
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This Phase 1 study tests whether injecting your own (autologous) activated fat-derived stem cells into the brain is safe and potentially helpful for mild to moderate Alzheimer’s disease. The goal is to see how the treatment affects the brain and symptoms, using cells made from your own donated fat tissue.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 45 and 80 years old
- Have a diagnosis of mild to moderate Alzheimer’s disease
- Be able to do the study’s thinking tests well enough for enrollment
- Have no other medical conditions or brain problems that better explain your memory issues (no tumors causing dementia)
- Be in generally good health with long-term problems (other illnesses) controlled on stable medications for at least 3 months
- Have a caregiver/relative who can participate in the study’s caregiver requirements
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new stem cell treatment (called RB-ADSCs) that is injected into the fluid around your brain. It aims to see if these cells can help slow down memory loss and thinking problems in people with mild to moderate Alzheimer's disease.
This trial tests whether stem cells from donated fat tissue can help people with mild to moderate Alzheimer's disease. It combines infusions of these cells with standard care, and includes brain scans and memory tests to see if the treatment is safe and effective.
This trial is a follow-up for people who already received a single dose of RB-ADSC (a stem cell treatment) in an earlier study. It tests whether more doses, given through a small brain injection, are safe and might help with Alzheimer's.
This Phase 2 study tests whether sargramostim (a GM-CSF related medicine) is safe and can slow or improve Alzheimer’s symptoms. You might be a good fit if you have mild or moderate Alzheimer’s, positive amyloid testing, and can complete frequent visits with a close caregiver who knows you well.
This trial tests whether a gentle, non-invasive brain stimulation (transcranial alternating current) can improve memory and thinking in people with early Alzheimer's or mild memory problems. It involves regular sessions of stimulation and check-ups over several months.
This trial tests a new nasal drop treatment made from stem cells for people with Alzheimer's, Parkinson's, multiple system atrophy, Lewy body dementia, frontotemporal dementia, or ALS. The drops may help slow disease progression by delivering tiny healing particles directly to the brain through the nose.
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