Testing pressure support to ease breathing muscle work
Part of Lungs & breathing clinical trials.
This trial looks at a breathing-support setting that may reduce the effort of your breathing muscles while you’re coming off a ventilator. It’s meant for people who have been on a breathing machine for more than 24 hours during the “weaning” phase.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are on a ventilator and have been intubated (tube in the windpipe) for more than 24 hours.
- You are in the ventilator weaning phase (doctors are trying to reduce/stop ventilator support).
- You do not have a bleeding problem (for example, blood clotting tests are not too high and platelets are not too low).
- Your circulation is stable (you are not needing high doses of blood-pressure medicine).
- You do not have very severe lung disease (lung-function measure is above the trial’s cut-off).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is looking at ways to improve non-invasive ventilation, which is breathing support given without a breathing tube. You may be invited if you’re already receiving this kind of support and you agree to take part.
This study tests a new way to adjust the breathing machine settings for patients who are awake and breathing on their own but still need support. The goal is to avoid giving too much help, which can make the breathing muscles weak.
This study tests if slowly reducing the breathing support from a ventilator can strengthen a patient's own breathing muscles. It may help patients who are still on the ventilator but stable enough to start building endurance.
This trial tests a new way of adjusting breathing machine support based on how hard you are breathing. It may help people with low oxygen levels who need a ventilator.
This study tests a special breathing therapy for intensive care patients who are having trouble coming off the ventilator. If you have weak muscles or a weak cough, the therapy aims to strengthen your breathing so you can recover faster.
This trial compares two ways of adjusting the breathing machine to help patients come off it more smoothly. It uses a special measurement (airway occlusion pressure) to guide settings, which may help you breathe on your own faster.
Hear when a new Acute Respiratory Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.