Study of targeted drugs for HER2-positive advanced stomach cancer
Part of Cancer, Digestive system clinical trials.
This Phase 2 trial tests whether SHR-A1811—given with other medicines—works safely and effectively for people with advanced stomach or gastroesophageal junction cancer that has high HER2. It may help shrink tumors or slow cancer growth, especially if previous treatment didn’t work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 to 75 years old, and you can be male or female
- Your stomach (or stomach/food-pipe junction) cancer must be adenocarcinoma that cannot be removed by surgery or has spread
- Your tumor must test positive for HER2 (a specific marker on cancer cells)
- You must have the right treatment situation: Phase Ib includes people who failed or couldn’t tolerate prior standard therapy (or had no prior drug treatment); Phase II is for people who have not had cancer drug treatment yet
- Your daily function must be good (ECOG 0–1) and your expected survival is at least 3 months
- Your blood and organ tests (bone marrow, liver, kidneys) need to meet study safety levels
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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