Clin2
NCT05676190Possibly a fitRecruiting

Cell therapy using your own immune cells for colorectal cancer

Colorectal Cancer

Part of Cancer, Digestive system clinical trials.

This trial studies an immune cell treatment made from your own blood cells to treat colorectal cancer that has spread or progressed. You may be eligible if you have stage III–IV disease that can be measured on scans and if standard treatments have not worked or couldn’t be tolerated.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
80 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You’re between 18 and 70 years old
  • You have colorectal cancer that is stage III or IV
  • You have at least one tumor spot that can be measured on scans (outside the brain)
  • You’ve tried at least one or two standard treatments before, or they stopped working or couldn’t be tolerated
  • Your doctor expects you can live at least 90 more days and that your major organs work well

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06530303Recruiting· Phase 1/Phase 2
Personalized immune cell therapy for colorectal cancer

This trial tests a treatment made from your own immune cells (called TILs) that are taken from your tumor, grown in a lab, and given back to you along with immunotherapy. It is for people with advanced colon or rectum cancer who have run out of standard options.

Beijing, Beijing Municipality
NCT07343791Recruiting· Early Phase 1
DC-CIK cell therapy plus three drugs for advanced colorectal cancer

This trial tests a combination of immune cells (DC-CIK) and three cancer drugs (epaloliposide, vortexil, and regorafenib) as a third-line treatment for people with advanced colorectal cancer that has spread. It aims to see if this mix is safe and helps shrink tumors or slow the cancer's growth.

Nanjing, Jiangsu
NCT06434376Enrolling by invitation· Early Phase 1
Personalized immune therapy for ctDNA-positive colorectal cancer

This trial tests a personalized immune therapy (like a custom vaccine) for people with colorectal cancer that has a positive ctDNA MRD test after surgery. It aims to use the body's own immune system to target any remaining cancer cells and prevent the cancer from coming back.

Wenzhou, Zhejiang
NCT06545630Recruiting· Phase 1
Personalized immune cell vaccine for colorectal cancer with liver spread

This trial tests a personalized vaccine made from your own immune cells (dendritic cells) that are trained to recognize colorectal cancer. It is for people who had surgery for colorectal cancer that spread to the liver and are now at high risk for the cancer returning.

Chengdu, Chengdu/Sichuan
NCT06504901Not yet recruiting
Immunotherapy and chemo for colorectal cancer with liver spread

This trial tests a combination of an immunotherapy drug (PD-1 inhibitor), growth factors, and chemotherapy (CapeOX) for people whose colorectal cancer has spread only to the liver. The goal is to see if this combination shrinks the tumors enough to allow surgery to remove them completely.

NCT06819280Recruiting
Immune cells for advanced colorectal cancer after first treatment

This trial tests whether your own immune cells, called tumor-infiltrating lymphocytes (TILs), can be grown in a lab and given back to you to fight advanced colorectal cancer. It is for people whose cancer has continued to grow after their first round of chemotherapy.

Shanghai, Shanghai Municipality

Hear when a new Colorectal cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.