Single-dose antibiotics for sudden watery diarrhea
Treatments studied
Part of Digestive system, Infections clinical trials.
This trial compares rifaximin or azithromycin (both antibiotics) taken as a single dose, with loperamide to control symptoms. It’s for people with recent, watery diarrhea who can be treated and followed as an outpatient, to see which option works better and is safer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re active-duty military and age 18–60
- You have watery diarrhea starting recently: under 96 hours, with at least 2–3 loose/liquid stools in 24 hours and symptoms like nausea, vomiting, cramps, or feeling like you must go
- You can be treated as an outpatient (you can be observed for up to about 23 hours if needed)
- You can return for follow-up and will stay in the country for at least 7 days
- You have no allergies to rifamycin antibiotics, macrolide antibiotics (like azithromycin), or loperamide
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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