Rifaximin plus NAC for IBS with diarrhea
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether a combination of two medications—rifaximin (a gut antibiotic) and NAC (a supplement that helps break down mucus)—can reduce belly pain and diarrhea in people with IBS whose symptoms are not well controlled. It may be an option if other treatments haven't worked well enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and not pregnant or breastfeeding.
- You have been diagnosed with IBS where diarrhea is the main symptom (not constipation).
- Your IBS symptoms (like belly pain, loose stools, or urgent need to go) are still present despite any treatments you've tried.
- You do not have asthma, inflammatory bowel disease, celiac disease, or a history of certain stomach surgeries.
- You have not taken antibiotics in the last month, and you are not currently using the study drugs (rifaximin or NAC).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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