Apixaban to prevent blood clots in outpatient brain tumor patients
Treatments studied
Part of Cancer, Heart & circulation clinical trials.
This trial tests whether apixaban, a blood thinner, can prevent dangerous blood clots in people with a certain type of malignant brain tumor who are getting radiation and chemotherapy. It may help lower the risk of clots like leg clots or lung clots.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have malignant glioma that is WHO grade 4 (like glioblastoma or astrocytoma), confirmed by recent biopsy or surgery
- You are 18 years or older and able to give informed consent
- Your overall ability to do daily activities is moderate to strong (Karnofsky score 60–100)
- Your kidney function and blood counts meet study lab thresholds (platelets ≥ 100,000 and GFR ≥ 25)
- You are planning to start radiation and chemotherapy as part of your treatment
- You have not had a DVT, pulmonary embolism, or cerebral vein clot in the last 6 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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