Topical imipramine with light treatment for skin pain relief
Treatments studied
Part of Cancer, Skin clinical trials.
This Phase 1 study tests whether applying imipramine cream to the skin affects pain and effectiveness when combined with a light-based skin treatment (photodynamic therapy). It’s mainly looking at safety and early signs of benefit for people with certain sun-damaged skin areas.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your skin type must be “fair” (Fitzpatrick type I to III).
- You must have a doctor’s order to get the light treatment (PDT) on your face, scalp, or forearms.
- You must be willing to avoid extra sun and tanning beds on the treatment area.
- You cannot be taking certain antidepressants (tricyclics or SSRIs).
- You can’t have porphyria, be pregnant or nursing, have active rashes, or large tattoos where treatment will be.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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