Testing antidepressant creams for rosacea redness
Treatments studied
Part of Skin clinical trials.
This study tests if creams containing two antidepressants (imipramine and amitriptyline) can reduce skin redness caused by UV light in people with rosacea. It compares how the creams affect redness to see if they could be a new treatment option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have light to medium skin (Fitzpatrick types I–III).
- You have rosacea or are a healthy person without flushing/blushing (if you are a control participant).
- You are not taking imipramine, amitriptyline, or any similar antidepressant (oral or cream).
- You have not used anti-inflammatory creams or steroids in the past week or taken them by mouth recently.
- You don't have large tattoos on your back or arms (where the UV test will be done).
- You haven't used tanning beds in the last 3 months or had other light treatments recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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