Clin2
NCT05689645Possibly a fitRecruiting

Drug trial for liver injury or liver failure

Acute Liver FailureAcute-On-Chronic Liver Failure

Part of Digestive system clinical trials.

This Phase 2 trial tests an injection medicine (F573) to see if it can improve people with liver injury, drug-related liver damage, or liver failure. You may be screened with blood tests, liver stiffness measurements, and possibly symptom checks.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
97 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You are between 18 and 60 years old (or up to 65–70 depending on the stage).
  • You have liver injury or liver failure based on specific blood test patterns (including ALT and bilirubin levels).
  • Your abnormal liver blood tests have been happening for a limited time (for some groups, no more than 90 days/60 days).
  • You must use effective birth control from screening until 6 months after the last study drug dose.
  • You can sign the consent form and follow study visits and instructions (or a legal guardian/witness can sign if needed).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06916585Recruiting· Phase 2
Testing AS1501 for acute-on-chronic liver failure

This trial tests a new drug called AS1501 for people with acute-on-chronic liver failure (a sudden worsening of chronic liver disease). It aims to see if the drug can help improve liver function and reduce the need for a liver transplant. You may be eligible if you are in the early or middle stage of this condition and have a specific blood marker (high TRAIL level).

Shenzhen, Guangdong
NCT06890039Recruiting· Phase 2
Study of a new treatment for severe alcoholic hepatitis

This trial tests an experimental drug for people with severe alcoholic hepatitis that did not improve with steroids. Participants should have a moderate level of organ failure, but not require a breathing tube or kidney dialysis.

London, Greater London
NCT04597164Recruiting
Test a hepatitis B–targeted treatment for serious liver failure

This trial studies a combination approach called DPMAS and low-volume plasma exchange for people with hepatitis B–related acute-on-chronic liver failure. If you qualify, the goal is to improve your liver function and reduce serious complications from liver failure.

Guangzhou, Guangdong
NCT06884904Not yet recruiting· Phase 2/Phase 3
Stem cell infusion for liver failure from hepatitis B

This trial tests whether a stem cell infusion made from umbilical cord tissue can help people with severe liver failure caused by hepatitis B. The stem cells may reduce liver damage and improve recovery.

NCT07600788Recruiting· Phase 1
Liver Function and Safety Study of AHB-137 Injection

This study tests how a new investigational drug called AHB-137 moves through your body and affects safety in people with mild-to-moderate liver problems compared to people with normal liver function. The goal is to understand if the drug works safely in people whose livers don't work as well as they should.

Chongqing, Chongqing Municipality
NCT06891365Recruiting· Phase 1
Multiple doses of a new drug for fatty liver disease

This trial tests a new medication for people with fatty liver disease. It will see if the drug can reduce liver fat and improve liver health over several doses.

Harrow

Hear when a new Acute Liver Failure trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.