Clin2
NCT07600788Possibly a fitRecruiting

Liver Function and Safety Study of AHB-137 Injection

Chronic Hepatitis B

Treatments studied

Part of Digestive system, Immune system & allergy, Infections, Lungs & breathing clinical trials.

This study tests how a new investigational drug called AHB-137 moves through your body and affects safety in people with mild-to-moderate liver problems compared to people with normal liver function. The goal is to understand if the drug works safely in people whose livers don't work as well as they should.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
32 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • Age between 18–65 years old
  • Either mild-to-moderate liver dysfunction OR normal liver function (study compares the two groups)
  • Willing to use effective birth control if you can get pregnant
  • No liver cancer, organ transplant, or recent major surgery (within 3 months)
  • No HIV, hepatitis, or other serious infections
  • No use of certain medications in the past months, including blood thinners, immunosuppressants, or certain anti-cancer drugs

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07137910Recruiting· Phase 2
Study of AHB-137 for chronic hepatitis B

This trial tests a new injection called AHB-137 for people with chronic hepatitis B. It aims to see if the drug is safe and helps control the virus.

Beijing, Beijing Municipality
NCT07635186Recruiting· Phase 2
AHB-137 injection for treatment-naïve chronic hepatitis B

This study tests a new injection called AHB-137 in people with chronic hepatitis B who have never received antiviral treatment. The goal is to see if it can help reduce the hepatitis B virus in the body and improve liver health.

Beijing, Beijing Municipality
NCT07069569Recruiting· Phase 2
AHB-137 injection combined with other hepatitis B drugs

This study tests a new injection called AHB-137 combined with other hepatitis B drugs. It aims to see if the combination can better control the virus in people with chronic hepatitis B who are already on antiviral pills.

Beijing, Beijing Municipality
NCT07146100Recruiting
Long-term follow-up after AHB-137 treatment for hepatitis B

This study follows participants with chronic hepatitis B who previously responded to the drug AHB-137. The goal is to track long-term health and safety after their treatment.

Hefei, Anhui
NCT06425341Recruiting· Phase 2
Test injection to keep hepatitis B suppressed

This Phase 2 trial studies an injection (HRS-5635), either alone or with other medicines, to see if it is safe and helps keep chronic hepatitis B under control. It is for people who are already on standard hepatitis B antivirals and have low or undetectable viral levels.

Guangzhou, Guangdong
NCT07519330Recruiting· Phase 2
Testing HH-006 treatment for chronic hepatitis B

This study tests a new drug called HH-006 to see if it can help treat chronic hepatitis B infection. Participants will be grouped by their infection level, and the study checks whether the drug is safe and works to reduce the hepatitis B virus.

Chongqing, Chongqing Municipality

Hear when a new Chronic Hepatitis B trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.