Studying bile acid levels and genes in pregnancy itching
Part of Skin clinical trials.
This study looks at bile acid levels and possible genetic changes in people with persistent pregnancy itching. The goal is to better understand the cause of intrahepatic cholestasis of pregnancy and related pregnancy outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are older than 21 and have ongoing pregnancy itching (pruritus)
- Blood tests show signs of liver involvement, such as higher ALT/AST or higher bile acids
- You can understand the study and agree to sign consent before any study steps
- You plan to stay in the study through delivery (and allow follow-up after delivery)
- You are willing to share delivery and pregnancy outcome information
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at bile acid levels in pregnant women who have intrahepatic cholestasis of pregnancy (ICP), a liver condition that causes itching and can affect the baby. It also includes two control groups: healthy pregnant women and healthy non-pregnant women for comparison.
This study tests a medication called maralixibat to see if it is safe and well-tolerated in pregnant women with intrahepatic cholestasis of pregnancy (ICP), a liver condition that causes severe itching. Participation may help manage your symptoms and provide important information about this potential treatment.
This study tests a medication called maralixibat for treating intrahepatic cholestasis of pregnancy (ICP), a liver condition that causes severe itching and can affect the baby. The goal is to see if it safely lowers bile acids and improves outcomes for you and your baby.
This study looks at how a pregnancy liver condition (intrahepatic cholestasis) affects the baby's breathing after birth. It compares newborns whose mothers had this condition (and took medication for it) with newborns whose mothers did not have any liver issues during pregnancy.
This study looks at whether a pregnancy liver condition called intrahepatic cholestasis of pregnancy is linked with chronic inflammation in the placenta. It may help doctors better understand risks and what to monitor during pregnancy.
This study looks at whether certain family-related genes make people more likely to develop liver or bile duct cancers without a clear cause. If you had surgery or a transplant for one of these cancers and have had unexplained high liver enzymes or itching, this trial may help find genetic clues.
Hear when a new Intrahepatic Cholestasis of Pregnancy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.