Inflammation and blood flow in widened heart arteries
Part of Heart & circulation clinical trials.
This study looks at markers of inflammation and blood flow (ischemia) in people with a rare condition called coronary artery ectasia, where the heart arteries are widened instead of narrowed. You may qualify if you are already scheduled for a routine angiogram to check for heart artery problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have suspected coronary artery disease and are scheduled for a routine coronary angiogram (a test that uses dye and X-rays to see your heart arteries).
- You have never had a heart attack (myocardial infarction) or been diagnosed with cardiomyopathy (a weakened heart muscle).
- You have not had a recent heart attack or unstable angina (acute coronary syndrome) in the last few weeks.
- You do not have severe kidney disease (kidney failure or on dialysis).
- You have not had bypass heart surgery (CABG) in the past.
- You are able to walk and do daily activities without major physical limitations.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study is a registry (a structured way of collecting health information) for people suspected of coronary artery disease who are having an elective heart angiogram. It helps researchers better understand coronary artery ectasia and how it shows up in everyday patients.
This trial tests two different blood-thinner strategies for people who have had a recent heart attack and also have a widened artery (ectasia) in the heart. The goal is to find the safest and most effective way to prevent another heart attack or clot.
This is a “registry” study that collects health information about people who have isolated coronary artery ectasia (an abnormal dilation of a heart artery). It may help doctors better understand what to expect and how these conditions relate to symptoms like chest pain or heart attacks.
This study looks at inflammation in blood vessels of people who have chest pain or signs of heart problems but whose coronary arteries (the main blood vessels supplying the heart) don't have significant blockages. Researchers will study blood samples and heart imaging to better understand why some people have symptoms even without major artery blockages.
This trial studies how to treat people who recently had acute coronary symptoms (like a heart attack or unstable angina) and who also have enlarged or swollen coronary artery segments (coronary ectasia or true aneurysm). It may help by testing a specific approach for reducing risks related to these abnormal artery changes.
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